Objective

2

We aimed to (i) explore the proportion of complication of cardiovascular risk-related diseases

the degree of thickening of the carotid intima media thickness (IMT) the detection rate of plaques

and the distribution law of traditional Chinese medicine (TCM) syndrome elements in different coronary artery lesions

(ii) analyze the factors influencing coronary artery lesions

and (iii) explore the theory of blood vessels.

Methods

2

A cross-sectional retrospective analysis including 227 patients admitted to the Department of Cardiovascular Medicine of The First Affiliated Hospital of Guangzhou University of Chinese Medicine between August 2021 and October 2021 who were diagnosed by coronary angiography because of chest pain was conducted.The patients were divided into four groups according to the Gensini score: the no stenosis group

the mild stenosis group

the moderate stenosis group and the severe stenosis group.The proportion of cardiovascular risk-related diseases

the distribution law of TCM syndrome elements

the carotid IMT thickening degree and the distribution law of plaque in different degrees of coronary stenosis were analyzed

and the factors related to coronary stenosis were analyzed by multi-classification logistic regression.

Results

2

The proportion of moderate coronary artery disease with diabetes and dyslipidemia was the highest in the moderate stenosis group.The analysis of syndrome elements showed that the factors related to disease location were all in the heart.Among the TCM syndrome elements

the proportion of heat toxin in the moderate stenosis group was the highest

while the proportions of phlegm-turbidity

qi stagnation and qi deficiency were the highest in the no stenosis group.Among the 227 patients who underwent coronary angiography

only 139 patients underwent carotid artery ultrasound examination.There are differences in the distribution of the degree of thickening in left IMT and right IMT and in the presence of plaques

which difference is statistically significant (

P

<

0.01).In the no stenosis group

the proportion of left IMT and right IMT

<

1.0 mm and without plaques was the highest.In the severe stenosis group

the proportion of right IMT 1.0~1.5 mm or left and right IMT

>

1.5 mm

with plaques was the highest

and decreased gradually in the moderate

mild and no stenosis groups.The proportion of left IMT 1.0~1.5 mm was the highest in the moderate stenosis group

next to that in the severe stenosis group

decreased gradually in the mild and no stenosis groups.Multi-classification logistic regression showed that the main factors affecting coronary artery stenosis were complicated with dyslipidemia

heat toxin and right IMT.

Conclusion

2

Dyslipidemia

Carotid artery and coronary artery plaques damage due to the blood vessels.Dyslipidemia

heat toxin

right IMT thickening are factors influencing coronary artery stenosis.The concept of disease prevention and treatment based on blood lipid level

carotid ultrasound combined with TCM syndrome differentiation is put forward

which aims to identify the disease in a non-invasive way

prevent it before it aggravates

and prevent it from spreading.