There are uncertainness in science of Chinese medicine （CM） because the infiltration of Chinese ancient culture

so the quintessence of CM is difficult to grasp. The CM circles and even the whole scientific circles are paying attention to the research of standardization of syndrome manifestations along with the scientific development. Set pair analysis （SPA） is a kind of systematic theory and method with related number of a+bi+cj for processing the uncertainness caused by confused

randomly

incomplete intermediary and information. SPA takes certainness and uncertainness as a certain and uncertain sameness-difference-counter system and processes it dialectically and mathematically. SPA is used in the research of syndrome manifestations of CM from the quantitative angle to understand the essence of certainness of CM at a systematic level. The research will improve the theoretical study of standardization of syndrome manifestations and objectivity of CM to a great extent.