1.北京中医药大学东直门医院 北京 100700
2.北京中医药大学生命科学学院
张馨予,女,在读博士生
#姜苗,男,博士,主任医师,博士生导师,主要研究方向:中西医结合防治恶性肿瘤及其相关性疾病,E-mail:doctorjiang@139.com
纸质出版日期:2023-02-28,
网络出版日期:2022-10-26,
收稿日期:2022-05-28,
移动端阅览
张馨予, 李萌菲, 王桂青, 等. 张锡纯论治“血枯病”发微[J]. 北京中医药大学学报, 2023,46(2):176-180.
ZHANG Xinyu, LI Mengfei, WANG Guiqing, et al. Zhang Xichun’s treatment of blood depletion disease[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(2):176-180.
张馨予, 李萌菲, 王桂青, 等. 张锡纯论治“血枯病”发微[J]. 北京中医药大学学报, 2023,46(2):176-180. DOI: 10.3969/j.issn.1006-2157.2023.02.006.
ZHANG Xinyu, LI Mengfei, WANG Guiqing, et al. Zhang Xichun’s treatment of blood depletion disease[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(2):176-180. DOI: 10.3969/j.issn.1006-2157.2023.02.006.
血枯病源自《黄帝内经》,临床以胸胁胀满、纳食不佳、咳血、便血、尿血为主要表现,甚则女子出现闭经,方用四乌鲗骨一藘茹丸治之。后世医家对血枯病的病因病机、治疗重点、遣方用药众说纷纭,认为四乌鲗骨一藘茹丸中海螵蛸收敛固涩,茜草通经活血,其功效相悖,临床难以把握,以致经典良方险些湮没。及至民国,张锡纯守《黄帝内经》之本,钩沉拾遗,衷中参西,在其代表作《医学衷中参西录》中对血枯病的创新大体可归纳为古病新方、古方新用。一方面,本团队试从古病新方的角度整理了张锡纯为治疗血枯病创制的理冲汤、理冲丸、资生汤、资生通脉汤、醴泉饮、化瘀通经散、十全育真汤等新方,他认为血枯病的病机为心郁脾虚、血分瘀阻,治疗原则为扶正黜邪,以斡旋坤土为基,兼以祛瘀化滞、滋阴降火。另一方面,本团队试从古方新用角度探讨张锡纯打破海螵蛸、茜草药效相悖的局限,利用药对化滞、收涩的双向调节作用,治疗带下病、崩漏、淋病、便血、尿血等,拓宽了古方的适应症。以上两点可为临床治疗妇科、男科等疾病提供新思路。
Blood depletion disease originates from
Huangdi Neijing
. The clinical symptoms are fullness and discomfort in the chest and hypochondrium
poor diet
hemoptysis
blood in the urine
blood in the stool
even in woman with amenorrhea. The
Siwuzeigu Yiluru
Pill can be used to treat blood depletion disease
although physicians of later generations had different opinions on the etiology
pathogenesis
treatment
and prescription of blood depletion disease. It was even believed that the cuttlefish bone in
Siwuzeigu Yiluru
Pill has astringent effects
while India madder root is used to promote blood circulation. However
astringent is contrary to the effect of promoting blood circulation
and difficult to grasp clinically
the classic prescription almost disappeared. Zhang Xichun
a famous physician of the Republic of China
inherited the spirit of
Huangdi Neijing
and integrated traditional Chinese medicine and Western medicine. He provided innovative research on blood depletion disease in his representative work
Records of Tradition Chinese and Western Medicine in Combination
which can be roughly summarized into two points as new prescriptions for ancient diseases and new use of ancient herbal prescriptions. Our team attempted to sort the new prescriptions created by Zhang Xichun to treat blood depletion disease
including
Lichong
Decoction
Lichong
Pill
Zisheng
Decoction
Zisheng Tongmai
Decoction
Liquan
Decoction
Huayu Tongjing
Powder
and
Shiquan Yuzhen
Decoction
from the perspective of new prescriptions for ancient diseases. He believed that stagnation of heart and spleen deficiency and blood stasis underlie the pathogenesis of blood depletion disease
and suggested that the most effective treatment would be to strengthen the vital energy and eliminate the pathogenic factor
while concurrently promoting digestion
removing blood stasis and removing stagnation
nourishing yin for reducing fire. However
we also aimed to discuss Zhang Xichun’s idea of removing the limitation of the contradictory efficacy of cuttlefish bone and India madder root in the new use of the ancient herbal prescription. We used the bidirectional regulating effect of the medicine to remove stagnation and astringency to treat diseases such as morbid vaginal discharge
metrorrhagia
difficulty and pain in micturition
hemafecia
and hematuria
which broadened the applicability of the ancient prescription. These points provide new ideas for the clinical treatment of gynecopathy and andrological disease
which broaden the applicability of the ancient prescription and have important guiding significance for clinical practice.
血枯病医学衷中参西录张锡纯古病新方古方新用
blood depletion diseaseRecords of Tradition Chinese and Western Medicine in CombinationZHANG Xichunnew prescriptions for ancient diseasesnew use of ancient herbal prescriptions
弓雪峰,崔红生,任培中,等.从“微瘀”防治间质性肺疾病早期病变思路[J].北京中医药大学学报,2020,43(3):248-251.
谢映庐.谢映庐医案[M].上海:上海科学技术出版社,2010:185-187.
唐宗海.血证论[M].魏武英,李佺,整理.北京:人民卫生出版社,2017:188.
张琦.素问释义[M]. 王洪图,点校.北京:科学技术文献出版社,1998:142.
黄元御.素问悬解[M].孙国中,方向红,校注.北京:学苑出版社,2008:211.
张景岳.类经[M].范志霞,校注.北京:中国医药科技出版社,2011:302.
郭杨.资生通脉汤加减治疗气滞血瘀型月经过少的临床观察[D].哈尔滨:黑龙江中医药大学,2014.
何烨.理冲汤加减治疗盆腔炎性疾病后遗症(慢性盆腔痛)的临床研究[D].南京:南京中医药大学,2020.
刘影.理冲汤加减治疗血瘀证卵巢巧克力囊肿的临床观察[D].哈尔滨:黑龙江中医药大学,2020.
祁君,冯硕,宋锟,等.理冲汤加减联合针刺治疗盆腔炎性疾病后遗症慢性盆腔痛的临床观察[J].中国临床医生杂志,2022,50(8):998-1001.
周琴,周帆,张筱骅.理冲汤加减联合TC方案治疗晚期卵巢癌临床研究[J].新中医,2020,52(9):39-43.
周易[M].郭彧,译注.北京:中华书局,2006.
何梦瑶.医碥[M].邓铁涛,刘纪莎,点校.北京:人民卫生出版社,1993:7.
张锡纯.医学衷中参西录[M].鲁瑛,梁宝祥,高慧,等,校注.太原:山西科学技术出版社,2009.
刘珍珠,钱柯宏,刘修超,等.“香入脾”理论发微[J].北京中医药大学学报,2022,45(11):1130-1134.
张志聪.黄帝内经素问集注[M].王宏利,吕凌,校注.北京:中国医药科技出版社,2014:137.
刘玉良.张锡纯法象药理理论探微[J].北京中医药大学学报,2021,44(12):1093-1097.
FISCHER TH,THATTE HS,NICHOLS TC,et al. Synergistic platelet integrin signaling and factor 12 activation in poly-N-acetyl glucosamine fiber-mediated hemostasis[J]. Biomaterials, 2005,26(27):5433-5443.
欧莉,韩猛,张艺耀,等.茜草治疗功能性子宫出血的止血机制研究[J].中国实验方剂学杂志,2015,21(21):152-155.
侯玉琴,高卫辉.固冲汤治疗青春期异常子宫出血的Meta分析[J].中医临床研究,2021,13(15):112-115.
徐慧军,张英杰,薛辉,等.安冲汤治疗月经过多经期延长的临床观察及研究[J].中华中医药学刊,2010,28(8):1696-1698.
臧传鑫,张婷婷,赵文歌,等.自拟固冲汤联合福乃得治疗冲任不固型缺铁性贫血临床观察[J].广州中医药大学学报,2018,35(1):13-18.
蒋鹏娜,高永祥,隋淑梅.加减固冲汤治疗脾肾气虚型IgA肾病的临床疗效观察[J].中国中医基础医学杂志,2016,22(4):574-576.
闫宇欣,张传方.理血汤加减治疗无症状性血尿30例临床观察[J].亚太传统医药,2016,12(24):149-150.
陈冬梅,李潇,朱文芳.清带汤治疗宫颈环形电切术后阴道排液过多35例疗效观察[J].新中医,2011,43(6):93-94.
王庆,王高元,孙志兴,等.运用张锡纯清肾汤加味治疗男科疾病验案4则[J].江苏中医药,2018,50(7):48-50.
0
浏览量
16
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构