Henoch-Schönlein purpura nephritis (HSPN) in children is an immune disorder disease characterized by skin purpura accompanied by hematuria with or without proteinuria. Because of an increasing incidence rate

its treatment and prevention are gradually attracting greater attention. According to its clinical symptoms

the disease is classified as "purpura wind" "edema" and "cloudy urine"

and it is believed that collaterals are involved in the occurrence of the disease. As a microstructure that cooperates with the collaterals to perform the functions of kidney filtration and circulation of qi

blood

and body fluids

the kidney xuanfu also plays an important role in the pathological process of HSPN. If the opening and closing of the kidney xuanfu are orderly

and the collaterals are circulating smoothly

the kidney function is normal

the renal collaterals are not disturbed by evil factors

and the disease only manifests as skin purpura. If the opening and closing of the kidney xuanfu are not controlled properly

and the collaterals are blocked

the renal collaterals will be damaged

which will lead to the occurrence of HSPN. In view of this

this article proposes that the occurrence and development of HSPN can be divided into three stages: (ⅰ) the collaterals are disturbed by pathogenic factors

and the kidney xuanfu is open; (ⅱ) the collaterals are empty

and the kidney xuanfu is not controlled; and (ⅲ) the xuanfu is closed

the collaterals and blood exhibit stasis

and fire generates and phlegm retention appears. In addition

our team initially explored the treatment principles and method of HSPN based on the principle of "calming the collaterals and clearing the xuanfu"

"nourishing the collaterals and regulating the xuanfu"

and "opening the xuanfu and dredging the collaterals" from the perspective of "the opening and closing of the kidney xuanfu

and the dredging and blocking of collaterals"

with a view to providing new ideas for clinical treatment.