1.河南中医药大学第一临床医学院 郑州 450003
2.河南中医药大学
陈冠廷,男,在读博士生
# 王剑锋,男,博士,讲师,研究方向:中医药防治老年病,E-mail:2816589787@qq.com
纸质出版日期:2023-06-30,
网络出版日期:2023-02-13,
收稿日期:2022-11-10,
移动端阅览
陈冠廷, 任珂, 王剑锋. 基于17 948篇中英文文献分析近20年中医药治疗慢性肾脏病研究热点与趋势[J]. 北京中医药大学学报, 2023,46(6):879-888.
CHEN Guanting, REN Ke, WANG Jianfeng. Research hotspots and trends of traditional Chinese medicine for chronic kidney disease 2002-2022 based on 17, 948 Chinese and English articles[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(6):879-888.
陈冠廷, 任珂, 王剑锋. 基于17 948篇中英文文献分析近20年中医药治疗慢性肾脏病研究热点与趋势[J]. 北京中医药大学学报, 2023,46(6):879-888. DOI: 10.3969/j.issn.1006-2157.2023.06.022.
CHEN Guanting, REN Ke, WANG Jianfeng. Research hotspots and trends of traditional Chinese medicine for chronic kidney disease 2002-2022 based on 17, 948 Chinese and English articles[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(6):879-888. DOI: 10.3969/j.issn.1006-2157.2023.06.022.
目的
2
对近20年公开发表的中医药治疗慢性肾脏病的相关研究进行文献计量学分析,探索该学科领域的发展现状及趋势,预测未来研究方向。
方法
2
计算机检索万方数据知识服务平台、中国国家知识基础设施、中国生物医学文献服务系统、维普网、Web of Science、Cochrane Library、PubMed、Embase数据库2002—2022年公开发表的关于中医药治疗慢性肾脏病的相关研究文献,经NoteExpress软件筛选后通过CiteSpace 5.8R3和VOSviewer软件对作者、机构、关键词进行共现、聚类及突现分析,绘制可视化知识图谱。
结果
2
共纳入文献17 948篇,包括中文文献14 593篇、英文文献3 355篇,发文量逐年攀升,趋势稳定;核心作者884位,包括中文作者362位、英文作者522位,该领域已形成了以多个关键学者为中心的稳定团体,且各机构间合作密切;研究热点前期多集中于名医经验、临床观察、证候分析,后期多集中于多组学方式探究慢性肾脏病生理病理机制与药物作用机制,涉及基础学科与生物信息分析、数据挖掘、网络药理学等新兴学科。
结论
2
中医药治疗慢性肾脏病领域研究发展态势稳定,临床研究方向从疗效观察逐渐发展为循证级别更高的随机平行对照研究,基础研究的力度与深度伴随时间推移不断增强,其中以代谢组学为切入点,探讨中医药通过自噬调控免疫应答、内质网应激、肠黏膜屏障及肠道菌群等方面干预慢性肾脏病病理进展或是近期及未来一段时间的重点研究方向。
Objective
2
We aimed to conduct bibliometric analysis on relevant studies published in the past 20 years on the treatment of chronic kidney disease (CKD) with traditional Chinese medicine
to explore the current situation and development trends
and predict the future research direction.
Methods
2
The relevant research literature on the treatment of CKD by traditional Chinese medicine published in the Wanfang database
CNKI
SinoMed
VIP
Web of Science
Cochrane Library
PubMed
and Embase database from 2002 to 2022 was searched. The articles were screened using NoteExpress software
and the authors
institutions
and keywords were identified by CiteSpace 5.8R3 and VOSviewer clustering and emergence analysis software
and a visual knowledge graph was drawn.
Results
2
A total of 17
948 articles were included
namely
14
593 Chinese and 3
355 English articles. The number of publications increased each year
and the trend was stable; there were 884 core authors
including 362 Chinese authors and 522 English authors. A stable group centered on a number of key scholars had been formed in this field
and there was close cooperation among institutions. In the early stage
most of the research focused on the experience of renowned practitioners
clinical observation
and syndrome analysis; and in the later stage
most of the research focused on basic disciplines
such as the physiological and pathological mechanism of CKD and the mechanism of drug action in a multi group context
as well as new emerging disciplines
such as bioinformatics analysis
data mining
and network pharmacology.
Conclusion
2
The CKD field is in a steady state of research development
and the direction of clinical development has gradually progressed from efficacy observation to more evidence-based
randomized parallel controlled studies. Basic research in terms of its strength and depth has been increasing over time
and metabolomics has been used as an entry point to explore the potential of traditional Chinese medicine to intervene in the pathological progression of CKD
through autophagy regulation of the immune response
endoplasmic reticulum stress
intestinal mucosal barrier
and intestinal flora
which are likely a key research direction in the near future.
慢性肾脏病知识图谱可视化分析中医药
chronic kidney diseaseknowledge graphvisual analysistraditional Chinese medicine
SANDY M, BETH FH. Complications of Kidney Disease[J]. Nurs Clin North Am,2018,53(4):579-588.
王霞,蒋松.国家慢性肾脏病全程管理中心(CKDMC)简介[J].肾脏病与透析肾移植杂志,2020,29(5):499-500.
YANG C,WANG H,ZHAO X,et al. CKD in China:evolving spectrum and public health implications[J]. Am J Kidney Dis,2020,76(2):258-264.
《中成药治疗优势病种临床应用指南》标准化项目组. 中成药治疗慢性肾脏病3~5期(非透析)临床应用指南(2020年)[J].中国中西医结合杂志,2021,41(3):261-272.
王正晶. NoteExpress实现文献计量分析的方法:以五种情报学核心期刊统计分析为例[J].情报科学,2013,31(10):80-82.
侯剑华,胡志刚. CiteSpace软件应用研究的回顾与展望[J].现代情报,2013,33(4):99-103.
VAN ECK NJ,WALTMAN L. Software survey: VOSviewer, a computer program for bibliometric mapping[J]. Scientometrics,2010,84(2):523-538.
宗淑萍. 基于普赖斯定律和综合指数法的核心著者测评——以《中国科技期刊研究》为例[J].中国科技期刊研究,2016,27(12):1310-1314.
毕晨,赵琦睿,朱琳. 基于文献计量的国际移民管理研究概况与发展趋势可视化分析[J].科学观察,2021,11(5):1-14.
刘金花,崔金梅. 基于VOSviewer的领域性热门研究主题挖掘[J].情报探索,2016,36(2):13-16.
胡少虎,张颖怡,章成志. 关键词提取研究综述[J].数据分析与知识发现,2021,5(3):45-59.
陈悦,陈超美,刘则渊,等. CiteSpace知识图谱的方法论功能[J].科学学研究,2015,33(2):242-253.
梁依敏,梁文心,杨鑫龙,等. 基于CiteSpace和VOSviewer的国内近30年来中医药治疗胃癌前病变研究的文献计量学分析[J]. 时珍国医国药,2022,33(3):752-755.
中华医学会肾脏病分会透析移植登记工作组. 1999年度全国透析移植登记报告[J]. 中华肾脏病杂志,2001,17(2):77-78.
XIE JY,CHEN N. Primary glomerulonephritis in China's mainland: an overview[J]. Contrib Nephrol, 2013,181(1):1-11.
EBERT T, NEYTCHEV O, WITASP A, et al. Inflammation and Oxidative Stress in Chronic Kidney Disease and Dialysis Patients [J]. Antioxid Redox Signal,2021,35(17):1426-1448.
QIAN Q. Inflammation: A Key Contributor to the Genesis and Progression of Chronic Kidney Disease.[J]. Contrib Nephrol, 2017,191(1):72-83.
SHI LH, SONG J, ZHANG XD, et al. Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients [J]. Exp Ther Med, 2013,6(2):532-536.
张路霞,赵明辉. 重视我国慢性肾脏病的疾病谱变迁及人群管理策略[J]. 中华内科杂志,2017,56(3):161-162.
中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)(下)[J]. 中国实用内科杂志,2021,41(9):757-784.
莫业南,李茵,揭西娜,等. 基于肠道菌群探讨补脾益肾方改善5/6肾切除大鼠肠道屏障延缓慢性肾脏病进展的作用机制[J]. 世界科学技术—中医药现代化,2022,24(4):1539-1548.
ANDRADE-OLIVEIRA V, AMANO MT, CORREA-COSTA M, et al. Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion [J]. J Am Soc Nephrol,2015,26(8):1877-1888.
余柯娜,倪兆慧,汪年松,等. 健脾清化方治疗脾虚湿热型慢性肾脏病3期的多中心随机对照临床观察[J]. 中国医学科学院学报,2016,38(6):686-695.
孟元,王悦芬,陈东,等. 清补地龟汤治疗气虚湿热型慢性肾脏病3期患者随机对照研究[J]. 实用医学杂志,2018,34(22):3810-3815.
徐娟,郭文燕,刘琳娜,等. 尿毒康合剂联合常规治疗对慢性肾脏病患者的临床疗效[J]. 中成药,2022,44(12):3848-3852.
解艳欢,张勉之. 补肾活血法联合非布司他对慢性肾脏病3~4期合并高尿酸血症患者的治疗效果[J]. 中国老年学杂志,2021,41(20):4435-4437.
樊威伟,张大宁. 张大宁从虚、瘀、湿、逆论治慢性肾功能衰竭经验[J]. 中医杂志,2019,60(11):916-919.
刘定承.国医大师邹燕勤教授辨治慢性肾衰医案的数据挖掘及核心处方的网络药理学研究[D]. 南京:南京中医药大学,2021.
高燕翔,张琪. 张琪教授调脾补肾法治疗慢性肾脏病经验[J]. 中华中医药杂志,2015,30(8):2786-2789.
盛广宇,张亚亨,徐子灵,等. 何立群运用清化祛瘀法治疗慢性肾脏病经验[J]. 上海中医药杂志,2022,56(5):19-21.
崔成姬,孙伟,何伟明,等. 孙伟教授“湿热伤肾”理论诊治慢性肾脏病经验介绍[J]. 世界科学技术—中医药现代化,2022,24(8):3094-3098.
张磊,金华,王东,等. 王亿平辨治慢性肾衰竭急性加重湿热证临证经验[J]. 中国中医基础医学杂志,2017,23(1):127-128.
刘旭生,揭西娜,卢钊宇,等. 补脾益肾法治疗慢性肾脏病的特色与优势[J]. 中国中西医结合肾病杂志,2018,19(6):471-472.
韩文贝,刘莹露,万毅刚,等. 慢性肾脏病肠道菌群失调的病理机制、治疗策略及中药的干预作用[J]. 中国中药杂志,2017,42(13):2425-2432.
刘旭生,张显龙,张燕媚. 中医药在慢性肾脏病全周期防治中的运用[J]. 中国中西医结合肾病杂志,2021,22(4):283-286.
0
浏览量
12
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构