中国中医科学院广安门医院 北京 100053
赵青,女,副主任医师
# 王蕾,女,博士,主任医师,硕士生导师,主要研究方向:中医药治疗呼吸系统疾病,E-mail:wanglei1@gamyy.cn
纸质出版日期:2023-10-30,
网络出版日期:2023-09-27,
收稿日期:2023-05-28,
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赵青, 王文洁, 王蕾. 放射组学直方图分析在中医药治疗肺磨玻璃结节疗效评价中的应用[J]. 北京中医药大学学报, 2023,46(10):1338-1344.
ZHAO Qing, WANG Wenjie, WANG Lei. Application of radiomics histogram analysis in efficacy evaluation of TCM treatment of pulmonary ground glass nodules[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1338-1344.
赵青, 王文洁, 王蕾. 放射组学直方图分析在中医药治疗肺磨玻璃结节疗效评价中的应用[J]. 北京中医药大学学报, 2023,46(10):1338-1344. DOI: 10.3969/j.issn.1006-2157.2023.10.002.
ZHAO Qing, WANG Wenjie, WANG Lei. Application of radiomics histogram analysis in efficacy evaluation of TCM treatment of pulmonary ground glass nodules[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1338-1344. DOI: 10.3969/j.issn.1006-2157.2023.10.002.
临床报道中医药成功治疗了多例肺结节患者,但由于这些缩小或消失的肺结节缺少病理资料,关于中医药治疗有效的到底是炎性结节还是早癌结节一直存在争论。目前,中医药治疗肺结节的疗效多采用通过计算机断层扫描技术(CT)得到的影像直径、CT衰减值、肿瘤模型积分等方法评价,不能全面反映肺结节进展情况。放射组学技术的发展为肺磨玻璃结节的定性诊断提供更全面的数据信息,其中,通过观察直方图的图形(层数及是否形成波形)、熵值、体积、质量及偏度的变化,既有助于判定肺磨玻璃结节良恶性,又可用于反映其进展情况,具有动态、直观和无创的优势,希望为客观评估中医药治疗肺结节疗效提供新方法。
In clinical reports
patients with pulmonary nodules have been treated successfully with traditional Chinese medicine (TCM). However
due to the lack of pathological data on the reduction or disappearance of pulmonary nodules
whether TCM is effective in treating inflammatory nodules or early-stage cancer nodules remains controversial. The evaluation of the efficacy of TCM intervention in pulmonary nodules is often based on metrics obtaining through computed tomography(CT) such as nodule diameter
CT value
and tumor model integration
which do not comprehensively represent the current status of pulmonary nodule progression. CT radiomics technology provides more comprehensive data for the qualitative diagnosis of ground glass pulmonary nodules. By analyzing the CT histogram parameters using artificial intelligence technology
such as graphics (layers and wave shape)
entropy
volume
mass
and skewness
benign and malignant nodules can be identified. It can also be used for evaluating the progress of the nodules
as it is dynamic
intuitive
and non-invasive
which maybe provide a new method for objectively evaluating the efficacy of TCM in treating pulmonary nodules.
肺结节磨玻璃结节放射组学直方图疗效评估
pulmonary nodulesground glass nodulesradiomicshistogramefficacy evaluation
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