基于“土克水”理论探讨肠道菌群与绝经后骨质疏松症的关系

李彤彤; 马玮玮; 熊勇; 周广文; 文峰

doi:10.3969/j.issn.1006-2157.2023.10.007

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基于“土克水”理论探讨肠道菌群与绝经后骨质疏松症的关系

理论研究 | 更新时间：2023-11-06

- 基于“土克水”理论探讨肠道菌群与绝经后骨质疏松症的关系
- Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"
- 北京中医药大学学报 2023年46卷第10期页码：1367-1373
- 作者机构：
  
  1.湖北中医药大学针灸骨伤学院　武汉　430061
  2.湖北中医药大学附属医院
- 作者简介：
  
  李彤彤，女，在读硕士生
  # 熊勇，男，博士，副教授，副主任医师，硕士生导师，主要研究方向：脊柱、骨与关节退行性疾病的中医药防治，E-mail：xiongyong1978@163.com
- 基金信息：
  
  国家自然科学基金青年基金项目(81904267);2022年度湖北省教育厅科学研究计划指导性项目(B2022107);湖北省中医药管理局2023—2024年度中医药科研项目(ZY2023Q005)
- DOI：10.3969/j.issn.1006-2157.2023.10.007
  中图分类号： R271.9
- 纸质出版日期：2023-10-30，
  
  网络出版日期：2023-08-14，
  
  收稿日期：2023-04-16，
- 稿件说明：
移动端阅览
李彤彤, 马玮玮, 熊勇, 等. 基于“土克水”理论探讨肠道菌群与绝经后骨质疏松症的关系[J]. 北京中医药大学学报, 2023,46(10):1367-1373.

LI Tongtong, MA Weiwei, XIONG Yong, et al. Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1367-1373.
李彤彤, 马玮玮, 熊勇, 等. 基于“土克水”理论探讨肠道菌群与绝经后骨质疏松症的关系[J]. 北京中医药大学学报, 2023,46(10):1367-1373. DOI： 10.3969/j.issn.1006-2157.2023.10.007.

LI Tongtong, MA Weiwei, XIONG Yong, et al. Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1367-1373. DOI： 10.3969/j.issn.1006-2157.2023.10.007.

摘要

绝经后骨质疏松症是一种女性在绝经期后发生的骨代谢疾病，中医学将其归属为“骨痿”“骨蚀”等范畴。近年来，绝经后骨质疏松症与肠道菌群关联的研究逐渐深入。本文以中医学五行生克思想为基础，引用李东垣《脾胃论》中的“脾病则下流乘肾，土克水，则骨乏无力，是为骨蚀”观点，提出“土克水”致痿的理论。基于该理论基础，本文探讨脾虚、肾虚、痰浊三者在绝经后骨质疏松症病理过程中所起的作用，并阐释肠道菌群在其中的媒介角色。由此提出“脾土－肠道菌群－肾水－绝经后骨质疏松症”完整治疗链，为临床治疗绝经后骨质疏松症提供新的思路。

Abstract

Postmenopausal osteoporosis is a bone metabolism disease that occurs in women after menopause and is categorized in Chinese medicine as "bone flaccidity" and "bone erosion". In recent years

postmenopausal osteoporosis has been closely associated with studies on intestinal flora. Based on the generating-restricting relationship between the five elements in Chinese medicine and LI Dongyuan’s view that "when the spleen is sick

water-dampness flows downward to the kidney

and when the earth restricts water

the bones become weak and feeble

resulting in bone erosion" in

Piwei Lun

this article puts forward the theory that "earth restricting water" causes flaccidity. Building upon this theoretical foundation

we explore the roles of spleen deficiency

kidney deficiency

and phlegm turbidity in the pathologic process of postmenopausal osteoporosis

while highlighting the role of intestinal flora as a mediator in this process. We propose a comprehensive therapeutic approach involving the interplay of "spleen earth-intestinal flora-kidney water-postmenopausal osteoporosis"

which offers a new perspective for the clinical treatment of postmenopausal osteoporosis.

关键词

土克水肠道菌群绝经后骨质疏松症脾胃论

Keywords

earth restricting waterintestinal florapostmenopausal osteoporosisPiwei Lun

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