浙江中医药大学附属第一医院/浙江省中医院 杭州 310006
Prof. ZHOU Yuhong, Chief Physician, Doctoral Supervisor. The First Affiliated Hospital of Zhejiang Chinese Medical University/Zhejiang Provincial Hosptial of Chinese Medicine, No.54, Youdian Road, Hangzhou 310006. E-mail: zyhblood@163.com
纸质出版日期:2023-10-30,
网络出版日期:2023-08-11,
收稿日期:2023-03-09,
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周郁鸿. 中医药治疗慢性再生障碍性贫血研究述评[J]. 北京中医药大学学报, 2023,46(10):1461-1466.
ZHOU Yuhong. Comment on the research of chronic aplastic anemia treatment with traditional Chinese medicine[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1461-1466.
周郁鸿. 中医药治疗慢性再生障碍性贫血研究述评[J]. 北京中医药大学学报, 2023,46(10):1461-1466. DOI: 10.3969/j.issn.1006-2157.2023.10.019.
ZHOU Yuhong. Comment on the research of chronic aplastic anemia treatment with traditional Chinese medicine[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(10):1461-1466. DOI: 10.3969/j.issn.1006-2157.2023.10.019.
再生障碍性贫血是一种骨髓造血衰竭性疾病,以骨髓造血干细胞减少和全血细胞减少为特征。本病归属于中医学的“血证”“虚劳”“髓枯”“血虚”等范畴。近年来,再生障碍性贫血的发病率逐渐升高,但现有西医治疗手段有限,且存在长期疗效欠佳、不良反应大等局限性,而中医药在该病的治疗中具有独特的优势。中医药治疗再生障碍性贫血的研究始于20世纪50年代,至今已发展70余年。经过众多医家理论与实践的探索,逐渐形成了以补肾为核心,健脾益气、活血化瘀、泻火调肝、祛痰为辅的基本治则。本文围绕再生障碍性贫血理论溯源、中医证候类型演变、治法研究、中医药实验进展进行论述,并针对目前存在的问题提出建议和展望,以期为中医药治疗再生障碍性贫血的蓬勃发展添砖加瓦。
Aplastic anemia is a bone marrow hematopoietic failure disease
characterized as a decrease in bone marrow hematopoietic stem cells and pancytopenia. This disease belongs to the categories of "blood syndrome"
"deficiency and fatigue"
"marrow necrosis"
and "blood deficiency" in traditional Chinese medicine. In recent years
the incidence rate of aplastic anemia has gradually increased
but the existing western medicine treatment methods are limited
with poor long-term efficacy and larger adverse reactions. Conversely
traditional Chinese medicine has unique advantages in the treatment of this disease. The traditional Chinese medicine treatment of aplastic anemia began in the 1950 s and has developed for more than 70 years. Through the exploration of many physicians theory and practice
the basic treatment principles have gradually been formed
with tonifying the kidney as the core strategy
and with strengthening the spleen and replenishing qi
activating blood circulation for removing blood stasis
purging fire and regulating the liver
and dispelling phlegm as auxiliary strategies. This article summarizes the theoretical origin
evolution of syndrome types
treatment research
and experimental progress of traditional Chinese medicine in the treatment of aplastic anemia
and puts forward suggestions for the existing problems in order to contribute to the development of traditional Chinese medicine in the treatment of aplastic anemia.
慢性再生障碍性贫血中医药研究进展
chronic aplastic anemiatraditional Chinese medicineresearch progress
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