1.浙江中医药大学基础医学院 杭州 310053
2.中国中医科学院中医临床基础医学研究所
雷舒扬,女,博士,助理研究员
# 王丽颖,女,博士,研究员,博士生导师,主要研究方向:中医药标准化及民间特色诊疗技术研究,E-mail:coldmoon_ly@163.com
纸质出版日期:2023-11-30,
网络出版日期:2023-08-25,
收稿日期:2023-05-25,
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雷舒扬, 王丽颖, 朱爱松. 从“因虚致郁,因郁化毒,因毒损心”探讨冠心病伴发抑郁状态的病机及治疗[J]. 北京中医药大学学报, 2023,46(11):1605-1610.
LEI Shuyang, WANG Liying, ZHU Aisong. Discussion of the pathogenesis and treatment of patients on coronary heart disease with depression based on the "depression due to deficiency, toxin due to accumulation of depression, and heart damage due to toxin"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(11):1605-1610.
雷舒扬, 王丽颖, 朱爱松. 从“因虚致郁,因郁化毒,因毒损心”探讨冠心病伴发抑郁状态的病机及治疗[J]. 北京中医药大学学报, 2023,46(11):1605-1610. DOI: 10.3969/j.issn.1006-2157.2023.11.017.
LEI Shuyang, WANG Liying, ZHU Aisong. Discussion of the pathogenesis and treatment of patients on coronary heart disease with depression based on the "depression due to deficiency, toxin due to accumulation of depression, and heart damage due to toxin"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023,46(11):1605-1610. DOI: 10.3969/j.issn.1006-2157.2023.11.017.
在现代“生物—心理—社会”医学模式下,冠心病伴发抑郁状态的“双心”疾病已成为研究热点,其核心病机要素可以概括为“虚、郁、毒”,即因虚致郁、因郁化毒、因毒损心。其中,“虚”主要责之于心胆气虚,为发病的根本内因;“郁”既包含广义的气机郁滞,又包含狭义的情志三郁(怒郁、思郁、忧郁),为病情进展的关键因素;“毒”为痰饮、瘀血等病理产物蕴久化生的“伏毒”,并在情志之郁的影响下暴发,继而损伤心脉、败坏形质,造成不可逆的心功能损伤,为冠心病伴发抑郁状态的最终结局,并以益气强心、调神壮胆,理气解郁、加强意疗,痰瘀毒同治、透达血脉为主要治法,以期为临床诊治冠心病伴发抑郁状态提供新思路。
Under the modern "biology-psychology-society" medical model
coronary heart disease with depression has become a research focus
and its core pathogenesis elements can be summarized as "deficiency
depression
and toxin"
that is
depression due to deficiency
toxin due to accumulation of depression
and heart damage due to toxin. "Deficiency" mainly refers to the qi deficiency of heart and gallbladder
the fundamental internal cause of the disease. "Depression" includes both the broad sense of qi stagnation and the narrow sense of three depression-related emotions (anger
depressive thinking
and anxiety)
which are key factors in the progression of the disease. "Toxin" refers to the accumulation and transformation of pathological products
such as phlegm and static blood
into the "latent toxin". Toxins emerge under the stimulation of emotional depression and damage the heart channels
corrupt the shape
and cause irreversible cardiac functional lesions
the final outcome of coronary heart disease with depression. The main treatment methods include supplementing qi
strengthening heart
regulating the mind and strengthening the gallbladder
regulating qi to relieve depression
strengthening mental therapy
treating phlegm
stasis
and toxins together to smooth the blood vessels. We hope to provide new ideas for the clinical diagnosis and treatment of coronary heart disease with depression.
冠心病伴发抑郁状态心胆气虚情志三郁内生毒邪毒损心脉
coronary heart disease with depressionqi deficiency of heart and gallbladderthree depression-related emotionsendogenous toxinstoxin damages the heart channels
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